Yamamoto Leucine 90 Tablets

1,000mg of l-leucine per tablet
The ‘anabolic’ amino acid par excellence, the most important of the three branched-chain amino acids (Bcaa)
Promotes protein synthesis
Helps counteract muscle catabolism

€17.65

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SKU: CPYMM111 Categories: All Products, Amino Acids/BCAA, Gym Supplements & Body Improvement, Magnesium, Minerals, Minerals by Name, Proteins and Food Supplements, Supplements & Vitamins, Vitamins Tags: Gluten Free, Lactose Free Brand: Yamamoto

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Yamamoto Leucine TABS 90 Tablets

The essential branched-chain amino acids (BCAAs), namely leucine, valine, and isoleucine, are fundamental constituents obtained from proteins. These amino acids, deemed essential as our body does not naturally produce them, must be incorporated into our diet. Initially, it was believed that all three BCAAs served a similar purpose. However, a growing body of literature has elucidated that leucine, even in isolation, possesses significant potency in activating protein synthesis, particularly when administered at an intake of approximately 3-4 grams.

Leucine, often referred to as ‘the queen of amino acids’ among the BCAAs, stands out as the principal key amino acid involved in muscle protein synthesis. It plays a pivotal role by directly activating the ‘mTOR’ enzymatic pathway, thereby stimulating protein synthesis and mitigating muscle catabolism. Numerous scientific studies have unequivocally demonstrated the anabolic effects of leucine. Notably, a specific study conducted by Pasiakos et al. revealed that the immediate post-training consumption of leucine led to a remarkable 33% increase in muscle protein synthesis, fostering an insulogenic effect.

The influence of leucine extends beyond protein synthesis, impacting glucose tolerance and insulin resistance in adipocytes. This multifaceted effect arises from the heightened efficiency and improved signaling and secretion of insulin in the pancreas. Thus, the ‘queen of amino acids,’ leucine, emerges not only as a key player in protein synthesis but also as a contributor to enhanced metabolic functions.

Nutritional information

Nutrition information	Per daily dose (3 tablets)

L-leucine	3 g

Ingredients: L-Leucine; bulking agents: cellulose, calcium phosphates, carboxymethylcellulose cross-linked sodium; anti-caking agents: magnesium salts of magnesium salts of fatty acids, silicon dioxide.

Directions: take 3 tablets a day with a glass of water.

Warnings

Do not exceed the recommended daily dose. Food supplements should not be used as a substitute of a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of reach of young children. Do not use if pregnant, in children or for prolonged periods without consulting a doctor. Keep in a cool, dry place at room temperature, away from heat sources and sunlight. Do not dump after use.

SCIENTIFIC REFERENCES

Stipanuk MH. Leucine and protein synthesis: mTOR and beyond. Nutr Rev. 2007 Mar;65(3):122-9. doi: 10.1111/j.1753-4887.2007.tb00289.x. PMID: 17425063.

Duan Y, Li F, Li Y, Tang Y, Kong X, Feng Z, Anthony TG, Watford M, Hou Y, Wu G, Yin Y. The role of leucine and its metabolites in protein and energy metabolism. Amino Acids. 2016 Jan;48(1):41-51. doi: 10.1007/s00726-015-2067-1. Epub 2015 Aug 9. PMID: 26255285.

Mero A. Leucine supplementation and intensive training. Sports Med. 1999 Jun;27(6):347-58. doi: 10.2165/00007256-199927060-00001. PMID: 10418071.

Martínez-Arnau FM, Fonfría-Vivas R, Cauli O. Beneficial Effects of Leucine Supplementation on Criteria for Sarcopenia: A Systematic Review. Nutrients. 2019 Oct 17;11(10):2504. doi: 10.3390/nu11102504. PMID: 31627427; PMCID: PMC6835605.

Plotkin DL, Delcastillo K, Van Every DW, Tipton KD, Aragon AA, Schoenfeld BJ. Isolated Leucine and Branched-Chain Amino Acid Supplementation for Enhancing Muscular Strength and Hypertrophy: A Narrative Review. Int J Sport Nutr Exerc Metab. 2021 May 1;31(3):292-301. doi: 10.1123/ijsnem.2020-
0356. Epub 2021 Mar 18. PMID: 33741748.

Gwin JA, Church DD, Wolfe RR, Ferrando AA, Pasiakos SM. Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit. Nutrients. 2020 Aug 15;12(8):2457. doi: 10.3390/nu12082457. PMID: 32824200; PMCID: PMC7469068.

Pasiakos SM, McClung JP. Supplemental dietary leucine and the skeletal muscle anabolic response to essential amino acids. Nutr Rev. 2011 Sep;69(9):550-7. doi: 10.1111/j.1753-4887.2011.00420.x. PMID: 21884134.

Yang J, Chi Y, Burkhardt BR, Guan Y, Wolf BA. Leucine metabolism in regulation of insulin secretion from pancreatic beta cells. Nutr Rev. 2010 May;68(5):270-9. doi: 10.1111/j.1753-4887.2010.00282.x. PMID: 20500788; PMCID: PMC2969169.

Leenders M, van Loon LJ. Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes. Nutr Rev. 2011 Nov;69(11):675-89. doi: 10.1111/j.1753-4887.2011.00443.x. PMID: 22029833.

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Yamamoto Leucine 90 Tablets

This product is currently out of stock!

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Free Cyprus Home Delivery for Orders Over €39

Yamamoto Leucine TABS 90 Tablets

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