Yamamoto Berberina , 30 Capsules

Berberine is a bitter-tasting, intensely yellow vegetable alkaloid found in the bark, roots, and stems of plants within the Berberis genus, such as the barberry (Berberis vulgaris L.). It is a quaternary benzo isoquinolino alkaloid present in the roots, stem, and bark of a plant commonly known as “Barberry.”

Barberry, belonging to the Berberidaceae family, is widespread in both Asia and Europe. Various species of this plant exist, with Berberis aristata L. being among the most utilized in Eastern Traditional Medicines. Berberine, the primary compound and the most extensively studied for its effects on the human organism, is accompanied by other essential substances such as vitamin C (ascorbic acid), vitamin K, flavonoids, flavonols, and coumarins.

This group of potent bioactive substances holds significant therapeutic potential. With over 500 studies supporting its properties, Berberine ranks among the most researched natural molecules. Traditionally used in Chinese and Ayurvedic medicine for centuries, Berberine has gained increasing interest in modern Western medicine due to its diverse bioactivities, including antioxidant, anti-diabetic, anti-diarrheal-antimicrobial, cardiovascular protective, neuroprotective, anti-obesity, and hepatoprotective effects. Current research focuses on its impact on type 2 diabetes and cardiovascular protection, particularly its cholesterol-lowering properties.

Berberine gained prominence due to its hypoglycemic effects comparable to metformin, a widely used oral antidiabetic for type 2 diabetes. This natural compound demonstrates the ability to lower blood sugar levels by acting on the enzyme AMPK, crucial in cellular energy homeostasis and glucose metabolism. Berberine increases insulin sensitivity, enhances glucose absorption, and regulates gluconeogenesis, collectively reducing blood glucose levels.

Beyond its role in diabetes, Berberine’s cardiovascular benefits are noteworthy. It effectively reduces cholesterol through various mechanisms, influencing PCSK9 expression, LDL-C receptor degradation, and cholesterol uptake by the liver. Moreover, Berberine decreases intestinal cholesterol absorption, promotes its fecal excretion, and limits triglyceride synthesis.

Berberine’s potential extends to lipid and cholesterol control, as evidenced by comprehensive meta-analyses. Additionally, its natural antioxidant properties combat oxidative stress, contributing to cellular aging prevention.

Berberine has a rich history of anti-infectious virtues, particularly in traditional medicines of Asia. It exhibits antibacterial actions against staphylococci, streptococci, and salmonellae, as well as antiamoebic and antiprotozoal effects against various parasites.

Nutritional information